PPARGAMMA2 IS A KEY DRIVER OF LONGEVITY IN THE MOUSE.

Ppargamma2 is a key driver of longevity in the mouse.

Aging involves a progressive Lifestyle physiological remodeling that is controlled by both genetic and environmental factors.Many of these factors impact also on white adipose tissue (WAT), which has been shown to be a determinant of lifespan.Interrogating a transcriptional network for predicted causal regulatory interactions in a collection of mou

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Phloretin Prevents Diabetic Cardiomyopathy by Dissociating Keap1/Nrf2 Complex and Inhibiting Oxidative Stress

Hyperglycemia induces chronic inflammation and oxidative stress in cardiomyocyte, which are the main pathological changes of diabetic cardiomyopathy (DCM).Treatment aimed at these processes may be beneficial in DCM.Phloretin (PHL), a promising natural product, has many pharmacological activities, such as anti-inflammatory, anticancer, and anti-oxid

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Clinical symptoms and surgical outcome of colloid cysts of the third ventricle: A multicenter retrospective study

Introduction: Colloid cysts of the third ventricle are benign brain lesions that may obstruct cerebrospinal fluid flow within the ventricular system and cause symptoms like headaches, deterioration of vision, and acute hydrocephalus.Research question: What is the clinical outcome of surgical treatment of third ventricle colloid cysts, and what fact

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